Antiproliferative activity of new benzimidazole derivatives.
نویسندگان
چکیده
منابع مشابه
Antiproliferative activity of new benzimidazole derivatives.
A series of new benzimidazole derivatives were synthesized and tested in vitro for possible anticancer activity. Their effect of proliferation into selected tumor cell lines at normoxia and hypoxia conditions was determined by WST-1 test. Additionally, apoptosis test (caspase 3/7 assay) was used to check the mode caused by the agents of cell death. Four of the examined compounds (7, 8, 13, 11) ...
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New aryl-hydrazinyl-1,3-selenazole and aroyl-hydrazonyl-1,3-selenazoles were synthesized via Hantzsch type condensation reactions of selenosemicarbazides with α-halogenocarbonyl derivatives, under classical versus microwave heating conditions. Excellent yields and shorter reaction times were obtained under irradiation conditions. The structures of the synthesized compounds were assigned based o...
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ژورنال
عنوان ژورنال: Acta Biochimica Polonica
سال: 2013
ISSN: 1734-154X,0001-527X
DOI: 10.18388/abp.2013_2003